Polymorphism in PfMRP1 (Plasmodium falciparum Multidrug Resistance Protein 1) Amino Acid 1466 Associated with Resistance to Sulfadoxine-Pyrimethamine Treatment

Sulfadoxine-pyrimethamine (SP) remains widely recommended for intermittent preventive treatment against Plasmodium falciparum malaria for pregnant women and infants in Africa. Resistance to SP is increasing and associated primarily with mutations in the P. falciparum dhfr (Pfdhfr) and Pfdhps genes....

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Detalhes bibliográficos
Main Authors: Dahlström, Sabina, Veiga, M. Isabel, Mårtensson, Andreas, Björkman, Anders, Gil, J. Pedro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2687199/
https://ncbi.nlm.nih.gov/pubmed/19364873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00091-09
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