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In Vivo Selection of Reduced Susceptibility to Carbapenems in Acinetobacter baumannii Related to ISAba1-Mediated Overexpression of the Natural bla(OXA-66) Oxacillinase Gene

Two clonally related Acinetobacter baumannii isolates, A1 and A2, were obtained from the same patient. Isolate A2, selected after an imipenem-containing treatment, showed reduced susceptibility to carbapenems. This resistance pattern was related to insertion of the ISAba1 element upstream of the nat...

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Détails bibliographiques
Auteurs principaux: Figueiredo, Samy, Poirel, Laurent, Croize, Jacques, Recule, Christine, Nordmann, Patrice
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2687192/
https://ncbi.nlm.nih.gov/pubmed/19307373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01663-08
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