Oral Administration of Memantine Prolongs Survival in a Transgenic Mouse Model of Amyotrophic Lateral Sclerosis

BACKGROUND AND PURPOSE: N-methyl-D-aspartate (NMDA)-mediated neurotoxicity and oxidative stress have been implicated in the etiology of amyotrophic lateral sclerosis (ALS). Memantine is a low-affinity, noncompetitive NMDA receptor antagonist that may protect against motor neuron degeneration. METHOD...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Joo, In-Soo, Hwang, Dong-Hoon, Seok, Jung-Im, Shin, Sang-Kun, Kim, Seung-Up
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Korean Neurological Association 2007
विषय:
Original Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2686946/
https://ncbi.nlm.nih.gov/pubmed/19513129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3988/jcn.2007.3.4.181
टैग : टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!

समान संसाधन