No effects of bosentan on microvasculature in patients with limited cutaneous systemic sclerosis

The endothelium-derived vasoconstrictor molecule endothelin-1 (ET-1) has been suggested to play a role in the pathogenesis of Raynaud’s phenomenon (RP) and systemic sclerosis (SSc). We studied the effect of bosentan on microvascular structure and function in patients with RP secondary to limited cut...

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Bibliografiske detaljer
Main Authors: Hettema, Martha E., Zhang, Dan, Stienstra, Ymkje, Smit, Andries J., Bootsma, Hendrika, Kallenberg, Cees G. M.
Format: Artigo
Sprog:Inglês
Udgivet: Springer-Verlag 2009
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2686804/
https://ncbi.nlm.nih.gov/pubmed/19350343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10067-009-1157-4
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