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ER membrane–bending proteins are necessary for de novo nuclear pore formation

Nucleocytoplasmic transport occurs exclusively through nuclear pore complexes (NPCs) embedded in pores formed by inner and outer nuclear membrane fusion. The mechanism for de novo pore and NPC biogenesis remains unclear. Reticulons (RTNs) and Yop1/DP1 are conserved membrane protein families required...

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Bibliografiska uppgifter
Huvudupphovsmän: Dawson, T. Renee, Lazarus, Michelle D., Hetzer, Martin W., Wente, Susan R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2686408/
https://ncbi.nlm.nih.gov/pubmed/19273614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200806174
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