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Insights into COPII Coat Nucleation from the Structure of Sec23•Sar1 Complexed with the Active Fragment of Sec31
The COPII vesicular coat forms on the endoplasmic reticulum from Sar1–GTP, Sec23/24 and Sec13/31 protein subunits. Here, we define the interaction between Sec23/24•Sar1 and Sec13/31, involving a forty-residue Sec31 fragment. In the crystal structure of the ternary complex, Sec31 binds as an extended...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2007
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2686382/ https://ncbi.nlm.nih.gov/pubmed/17981133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2007.10.006 |
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