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Insights into COPII Coat Nucleation from the Structure of Sec23•Sar1 Complexed with the Active Fragment of Sec31

The COPII vesicular coat forms on the endoplasmic reticulum from Sar1–GTP, Sec23/24 and Sec13/31 protein subunits. Here, we define the interaction between Sec23/24•Sar1 and Sec13/31, involving a forty-residue Sec31 fragment. In the crystal structure of the ternary complex, Sec31 binds as an extended...

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Detalhes bibliográficos
Main Authors: Bi, Xiping, Mancias, Joseph D., Goldberg, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2686382/
https://ncbi.nlm.nih.gov/pubmed/17981133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2007.10.006
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