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A Genome-Wide Screen for Regulators of TORC1 in Response to Amino Acid Starvation Reveals a Conserved Npr2/3 Complex

TORC1 is a central regulator of cell growth in response to amino acid availability, yet little is known about how it is regulated. Here, we performed a reverse genetic screen in yeast for genes necessary to inactivate TORC1. The screen consisted of monitoring the expression of a TORC1 sensitive GFP-...

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Bibliographic Details
Main Authors: Neklesa, Taavi K., Davis, Ronald W.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2686269/
https://ncbi.nlm.nih.gov/pubmed/19521502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000515
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