The NF-κB negative regulator TNFAIP3 (A20) is inactivated by somatic mutations and genomic deletions in marginal zone lymphomas

Unique and shared cytogenetic abnormalities have been documented for marginal zone lymphomas (MZLs) arising at different sites. Recently, homozygous deletions of the chromosomal band 6q23, involving the tumor necrosis factor alpha–induced protein 3 (TNFAIP3, A20) gene, a negative regulator of NF-κB,...

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Главные авторы: Novak, Urban, Rinaldi, Andrea, Kwee, Ivo, Nandula, Subhadra V., Rancoita, Paola M. V., Compagno, Mara, Cerri, Michaela, Rossi, Davide, Murty, Vundavalli V., Zucca, Emanuele, Gaidano, Gianluca, Dalla-Favera, Riccardo, Pasqualucci, Laura, Bhagat, Govind, Bertoni, Francesco
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Hematology 2009
Предметы:
Lymphoid Neoplasia
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2686142/
https://ncbi.nlm.nih.gov/pubmed/19258598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-08-174110
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