The NF-κB negative regulator TNFAIP3 (A20) is inactivated by somatic mutations and genomic deletions in marginal zone lymphomas

Unique and shared cytogenetic abnormalities have been documented for marginal zone lymphomas (MZLs) arising at different sites. Recently, homozygous deletions of the chromosomal band 6q23, involving the tumor necrosis factor alpha–induced protein 3 (TNFAIP3, A20) gene, a negative regulator of NF-κB,...

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Detalhes bibliográficos
Main Authors: Novak, Urban, Rinaldi, Andrea, Kwee, Ivo, Nandula, Subhadra V., Rancoita, Paola M. V., Compagno, Mara, Cerri, Michaela, Rossi, Davide, Murty, Vundavalli V., Zucca, Emanuele, Gaidano, Gianluca, Dalla-Favera, Riccardo, Pasqualucci, Laura, Bhagat, Govind, Bertoni, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2686142/
https://ncbi.nlm.nih.gov/pubmed/19258598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-08-174110
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