The NF-κB negative regulator TNFAIP3 (A20) is inactivated by somatic mutations and genomic deletions in marginal zone lymphomas

Unique and shared cytogenetic abnormalities have been documented for marginal zone lymphomas (MZLs) arising at different sites. Recently, homozygous deletions of the chromosomal band 6q23, involving the tumor necrosis factor alpha–induced protein 3 (TNFAIP3, A20) gene, a negative regulator of NF-κB,...

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Bibliographische Detailangaben
Hauptverfasser: Novak, Urban, Rinaldi, Andrea, Kwee, Ivo, Nandula, Subhadra V., Rancoita, Paola M. V., Compagno, Mara, Cerri, Michaela, Rossi, Davide, Murty, Vundavalli V., Zucca, Emanuele, Gaidano, Gianluca, Dalla-Favera, Riccardo, Pasqualucci, Laura, Bhagat, Govind, Bertoni, Francesco
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2009
Schlagworte:
Lymphoid Neoplasia
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2686142/
https://ncbi.nlm.nih.gov/pubmed/19258598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-08-174110
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