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Mosquitoes Put the Brake on Arbovirus Evolution: Experimental Evolution Reveals Slower Mutation Accumulation in Mosquito Than Vertebrate Cells

Like other arthropod-borne viruses (arboviruses), mosquito-borne dengue virus (DENV) is maintained in an alternating cycle of replication in arthropod and vertebrate hosts. The trade-off hypothesis suggests that this alternation constrains DENV evolution because a fitness increase in one host usuall...

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Hlavní autoři: Vasilakis, Nikos, Deardorff, Eleanor R., Kenney, Joan L., Rossi, Shannan L., Hanley, Kathryn A., Weaver, Scott C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685980/
https://ncbi.nlm.nih.gov/pubmed/19503824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000467
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