A Wnt7b-dependent pathway regulates the orientation of epithelial cell division and establishes the cortico-medullary axis of the mammalian kidney

The mammalian kidney is organized into a cortex where primary filtration occurs, and a medullary region composed of elongated tubular epithelia where urine is concentrated. We show that the cortico-medullary axis of kidney organization and function is regulated by Wnt7b signaling. The future collect...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yu, Jing, Carroll, Thomas J., Rajagopal, Jay, Kobayashi, Akio, Ren, Qun, McMahon, Andrew P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Company of Biologists 2009
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685965/
https://ncbi.nlm.nih.gov/pubmed/19060336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.022087
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