Cooperation of amphiregulin and insulin-like growth factor-1 inhibits Bax- and Bad-mediated apoptosis via a protein kinase C-dependent pathway in non-small cell lung cancer cells

Amphiregulin (AR) and insulin-like growth factor-1 (IGF1) are growth factors known to promote non-small cell lung cancer (NSCLC) survival. We have previously published that 1) AR and IGF1, secreted by H358 NSCLC cells, cooperate to protect those cells and H322 NSCLC cells from serum-starved apoptosi...

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Bibliographic Details
Main Authors: Hurbin, Amandine, Coll, Jean-Luc, Dubrez-Daloz, Laurence, Mari, Bernard, Auberger, Patrick, Brambilla, Christian, Favrot, Marie-Christine
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2005
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685917/
https://ncbi.nlm.nih.gov/pubmed/15767261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M413516200
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