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Montelukast in the treatment of duodenal eosinophilia in children with dyspepsia: Effect on eosinophil density and activation in relation to pharmacokinetics

BACKGROUND: We have previously demonstrated the clinical efficacy of montelukast in a randomized double-blind controlled cross-over trial in patients with dyspepsia in association with duodenal eosinophilia. The mechanism of this clinical response is unknown but could involve a decrease in eosinophi...

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Autori principali: Friesen, Craig A, Neilan, Nancy A, Schurman, Jennifer V, Taylor, Debra L, Kearns, Gregory L, Abdel-Rahman, Susan M
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685805/
https://ncbi.nlm.nih.gov/pubmed/19432972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-9-32
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