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Structures of the G81A mutant form of the active chimera of (S)-mandelate dehydrogenase and its complex with two of its substrates

(S)-Mandelate dehydrogenase (MDH) from Pseudomonas putida, a membrane-associated flavoenzyme, catalyzes the oxidation of (S)-mandelate to benzoylformate. Previously, the structure of a catalytically similar chimera, MDH-GOX2, rendered soluble by the replacement of its membrane-binding segment with t...

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Main Authors: Sukumar, Narayanasami, Dewanti, Asteriani, Merli, Angelo, Rossi, Gian Luigi, Mitra, Bharati, Mathews, F. Scott
Formato: Artigo
Idioma:Inglês
Publicado: International Union of Crystallography 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685731/
https://ncbi.nlm.nih.gov/pubmed/19465768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444909010270
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