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Role of Bound Zn(II) in the CadC Cd(II)/Pb(II)/Zn(II)-responsive Repressor

The Staphylococcus aureus plasmid pI258 cadCA operon encodes a P-type ATPase, CadA, that confers resistance to Cd(II)/Pb(II)/Zn(II). Expression is regulated by CadC, a homodimeric repressor that dissociates from the cad operator/promoter upon binding of Cd(II), Pb(II), or Zn(II). CadC is a member of...

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Detalhes bibliográficos
Main Authors: Kandegedara, Ashoka, Thiyagarajan, Saravanamuthu, Kondapalli, Kalyan C., Stemmler, Timothy L., Rosen, Barry P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685678/
https://ncbi.nlm.nih.gov/pubmed/19286656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M809179200
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