Regulation of Intracellular Cholesterol Distribution by Na/K-ATPase

Recent studies have ascribed many non-pumping functions to the Na/K-ATPase. We show here that graded knockdown of cellular Na/K-ATPase α1 subunit produces a parallel decrease in both caveolin-1 and cholesterol in light fractions of LLC-PK1 cell lysates. This observation is further substantiated by i...

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Bibliographic Details
Main Authors: Chen, Yiliang, Cai, Ting, Wang, Haojie, Li, Zhichuan, Loreaux, Elizabeth, Lingrel, Jerry B., Xie, Zijian
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2009
Subjects:
Membrane Transport, Structure, Function, and Biogenesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685670/
https://ncbi.nlm.nih.gov/pubmed/19363037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.003574
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