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In vitro selection of an archaeal RNase P RNA mimics natural variation

Archaeal and bacterial RNase P RNAs are similar in sequence and secondary structure, but in the absence of protein, the archaeal RNAs are much less active and require extreme ionic conditions for activity. To assess how readily the activity of the archaeal RNA alone could be improved by small change...

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Bibliographic Details
Main Authors: Williams, Daniel, Brown, James W.
Format: Artigo
Language:Inglês
Published: Heron Publishing 2004
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685577/
https://ncbi.nlm.nih.gov/pubmed/15810433
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