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A single C. elegans PUF protein binds RNA in multiple modes

PUF proteins specifically bind mRNAs to regulate their stability and translation. Here we focus on the RNA-binding specificity of a C. elegans PUF protein, PUF-11. Our findings reveal that PUF-11 binds RNA in multiple modes, in which the protein can accommodate variable spacings between two distinct...

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Autors principals: Koh, Yvonne Yiling, Opperman, Laura, Stumpf, Craig, Mandan, Arpita, Keles, Sunduz, Wickens, Marvin
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685523/
https://ncbi.nlm.nih.gov/pubmed/19369425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1545309
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