An extra double-stranded RNA binding domain confers high activity to a squid RNA editing enzyme

RNA editing by adenosine deamination is particularly prevalent in the squid nervous system. We hypothesized that the squid editing enzyme might contain structural differences that help explain this phenomenon. As a first step, a squid adenosine deaminase that acts on RNA (sqADAR2a) cDNA and the gene...

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Hauptverfasser: Palavicini, Juan Pablo, O'connell, Mary A., Rosenthal, Joshua J.C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685509/
https://ncbi.nlm.nih.gov/pubmed/19390115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1471209
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