Genetic dissection of a major mouse obesity QTL (Carfhg2): integration of gene expression and causality modeling

HG.CAST-(D9Mit249-D9Mit133) (HG9) congenic mice are homozygous for CAST/EiJ chromosome (Chr) 9 alleles from ∼9 to 84 Mbp on a C57BL6/J-hg/hg (HG) background. This region contains the carcass fat in high growth mice (Carfhg2) quantitative trait locus (QTL), and while its obesity-promoting effects hav...

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Detalhes bibliográficos
Main Authors: Farber, Charles R., Aten, Jason E., Farber, Emily A., de Vera, Vincent, Gularte, Rodrigo, Islas-Trejo, Alma, Wen, Pengzi, Horvath, Steve, Lucero, Michael, Lusis, Aldons J., Medrano, Juan F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685499/
https://ncbi.nlm.nih.gov/pubmed/19336533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.90245.2008
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