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Transdermal Lovastatin Enhances Fracture Repair in Rats

Statins have been shown to stimulate BMP2 transcription and bone formation. This raises the possibility that they could be useful for enhancing rates of fracture repair. Observational studies in patients treated with oral statins for lipid-lowering have been controversial. The likely reason for thei...

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Detalhes bibliográficos
Main Authors: Gutierrez, Gloria E, Edwards, James R, Garrett, Ian R, Nyman, Jeffry S, McCluskey, Brandon, Rossini, Gianni, Flores, Alda, Neidre, Daria B, Mundy, Gregory R
Formato: Artigo
Idioma:Inglês
Publicado em: Amer Soc Bone & Mineral Res. 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685484/
https://ncbi.nlm.nih.gov/pubmed/18597639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1359/JBMR.080603
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