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Thermodynamic basis of the enhanced specificity of structured DNA probes

Molecular beacons are DNA probes that form a stem-and-loop structure and possess an internally quenched fluorophore. When they bind to complementary nucleic acids, they undergo a conformational transition that switches on their fluorescence. These probes recognize their targets with higher specifici...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Bonnet, Grégoire, Tyagi, Sanjay, Libchaber, Albert, Kramer, Fred Russell
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 1999
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26854/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10339560/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.11.6171
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