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Thrombospondin-1 modulates VEGF-A-mediated Akt signaling and capillary survival in the developing retina

Microvascular development is often perceived to result from a balance of positive and negative factors that impact signaling for proliferation and survival. The survival signaling that results from hypoxia-induced VEGF-A has been well established, but the factors that antagonize this signaling have...

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Detalhes bibliográficos
Main Authors: Sun, Jingfang, Hopkins, Benjamin D., Tsujikawa, Kaoru, Perruzzi, Carole, Adini, Irit, Swerlick, Robert, Bornstein, Paul, Lawler, Jack, Benjamin, Laura E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685346/
https://ncbi.nlm.nih.gov/pubmed/19304944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01246.2008
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