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Targeted ablation of cardiac sympathetic neurons reduces resting, reflex and exercise-induced sympathetic activation in conscious rats

Cholera toxin B subunit conjugated to saporin (SAP, a ribosomal inactivating protein that binds to and inactivates ribosomes) was injected in both stellate ganglia to evaluate the physiological response to targeted ablation of cardiac sympathetic neurons. Resting cardiac sympathetic activity (cardia...

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Detalhes bibliográficos
Main Authors: Lujan, Heidi L., Palani, Gurunanthan, Chen, Ying, Peduzzi, Jean D., DiCarlo, Stephen E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685337/
https://ncbi.nlm.nih.gov/pubmed/19304949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00095.2009
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