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Localization of NAAG-related gene expression deficits to the anterior hippocampus in schizophrenia

N-acetyl aspartyl glutamate (NAAG) is an endogenous agonist at the metabotropic glutamate receptor 3 (mGluR3,GRM3) receptor and antagonist at the N-methyl D-aspartate (NMDA) receptor, both receptors important to the pathophysiology of schizophrenia. Glutamate carboxypeptidase II (GCPII), an enzyme t...

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Main Authors: Ghose, Subroto, Chin, Ronald, Gallegos, Analysa, Roberts, Rosalinda, Coyle, Joseph, Tamminga, Carol
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685203/
https://ncbi.nlm.nih.gov/pubmed/19403271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.schres.2009.03.038
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