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Attenuation of wild-type human influenza A virus by acquisition of the PA polymerase and matrix protein genes of influenza A/Ann Arbor/6/60 cold-adapted donor virus.

Wild-type influenza A viruses can be attenuated for humans by the acquisition of genes from the A/Ann Arbor/6/60 cold-adapted (ca) donor virus. Six-gene reassortants, that is, viruses containing the hemagglutinin and neuraminidase surface glycoprotein genes of the wild-type virus and the six remaini...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Clin Microbiol
Hauptverfasser: Snyder, M H, Clements, M L, De Borde, D, Maassab, H F, Murphy, B R
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1985
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC268513/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4056002/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jcm.22.5.719-725.1985
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