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Creation of the two isoforms of rodent NKG2D was driven by a B1 retrotransposon insertion

The mouse gene for the natural killer (NK) cell-activating receptor Nkg2d produces two protein isoforms, NKG2D-S and NKG2D-L, which differ by 13 amino acids at the N-terminus and have different signalling capabilities. These two isoforms are produced through differential splicing, but their regulati...

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Detalhes bibliográficos
Main Authors: Lai, C. Benjamin, Zhang, Ying, Rogers, Sally L., Mager, Dixie L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685100/
https://ncbi.nlm.nih.gov/pubmed/19304755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp174
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