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Long 3′-UTRs target wild-type mRNAs for nonsense-mediated mRNA decay in Saccharomyces cerevisiae

The nonsense-mediated mRNA decay (NMD) pathway, present in most eukaryotic cells, is a specialized pathway that leads to the recognition and rapid degradation of mRNAs with premature termination codons and, importantly, some wild-type mRNAs. Earlier studies demonstrated that aberrant mRNAs with arti...

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Hlavní autoři: Kebaara, Bessie W., Atkin, Audrey L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685090/
https://ncbi.nlm.nih.gov/pubmed/19270062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp146
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