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A Lipid Receptor Sorts Polyomavirus from the Endolysosome to the Endoplasmic Reticulum to Cause Infection

The mechanisms by which receptors guide intracellular virus transport are poorly characterized. The murine polyomavirus (Py) binds to the lipid receptor ganglioside GD1a and traffics to the endoplasmic reticulum (ER) where it enters the cytosol and then the nucleus to initiate infection. How Py reac...

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Detalhes bibliográficos
Main Authors: Qian, Mengding, Cai, Dawen, Verhey, Kristen J., Tsai, Billy
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685006/
https://ncbi.nlm.nih.gov/pubmed/19503604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000465
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