Anterograde Trafficking of G Protein-Coupled Receptors: Function of the C-Terminal F(X)(6)LL Motif in Export from the Endoplasmic Reticulum

We have reported previously that the F(X)(6)LL motif in the C termini is essential for export of α(2B)-adrenergic (α(2B)-AR) and angiotensin II type 1 receptors (AT1Rs) from the endoplasmic reticulum (ER). Here, we further demonstrate that mutation of the F(X)(6)LL motif similarly abolished the cell...

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Main Authors: Duvernay, Matthew T., Dong, Chunmin, Zhang, Xiaoping, Zhou, Fuguo, Nichols, Charles D., Wu, Guangyu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Pharmacology and Experimental Therapeutics 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2684921/
https://ncbi.nlm.nih.gov/pubmed/19118123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.108.051623
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