Long-Term Morphine Treatment Decreases the Association of μ-Opioid Receptor (MOR1) mRNA with Polysomes through miRNA23b

μ-Opioid receptor (MOR) mediates most of the pharmacological effects of opioid drugs. The expression of MOR is temporarily and spatially regulated at both the transcriptional and post-transcriptional levels. Long-term morphine treatment that induces tolerance does not alter MOR mRNA expression, sugg...

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Bibliografiske detaljer
Main Authors: Wu, Qifang, Zhang, Lei, Law, Ping-Yee, Wei, Li-Na, Loh, Horace H.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Pharmacology and Experimental Therapeutics 2009
Fag:
Accelerated Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2684920/
https://ncbi.nlm.nih.gov/pubmed/19144786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.108.053462
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