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A Putative Fe(2+)-bound Persulfenate Intermediate in Cysteine Dioxygenase

The common reactions of dioxygen, superoxide and hydroperoxides with thiolates are thought to proceed via persulfenate intermediates, yet these have never been visualized. Here we report a 1.4 Å resolution crystal structure of the Fe(2+)-dependent enzyme cysteine dioxygenase (CDO) containing this pu...

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Hlavní autoři: Simmons, Chad R., Krishnamoorthy, Kalyanaraman, Granett, Spencer L., Schuller, David J., Dominy, John E., Begley, Tadhg P., Stipanuk, Martha H., Karplus, P. Andrew
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2684787/
https://ncbi.nlm.nih.gov/pubmed/18847220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi801546n
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