Soluble ST2 Levels Are Associated with Bleeding in Patients with Severe Leptospirosis

BACKGROUND: Severe leptospirosis features bleeding and multi-organ failure, leading to shock and death. Currently it is assumed that both exaggerated inflammation and immune suppression contribute to mortality in sepsis. Indeed, several proinflammatory cytokines are reported to be induced during lep...

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Détails bibliographiques
Auteurs principaux: Wagenaar, Jiri F. P., Gasem, M. Hussein, Goris, Marga G. A., Leeflang, Mariska, Hartskeerl, Rudy A., van der Poll, Tom, van 't Veer, Cornelis, van Gorp, Eric C. M.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2009
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Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2684584/
https://ncbi.nlm.nih.gov/pubmed/19488407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0000453
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