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Double mutation (R124H, N544S) of TGFBI in two sisters with combined expression of Avellino and lattice corneal dystrophies

PURPOSE: The R124H mutation of the keratoepithelin gene (TGFBI) causes Avellino corneal dystrophy whereas the N544S mutation of this same gene gives rise to lattice corneal dystrophy. We now report two cases with both R124H and N544S mutations of TGFBI. METHODS: Genomic DNA and cDNA were isolated fr...

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Detalhes bibliográficos
Main Authors: Yamada, Naoyuki, Kawamoto, Koji, Morishige, Naoyuki, Chikama, Tai-ichiro, Nishida, Teruo, Nishioka, Mitsuaki, Okayama, Naoko, Hinoda, Yuji
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Vision 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2684562/
https://ncbi.nlm.nih.gov/pubmed/19461933
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