Molecular profiles of Quadriceps muscle in myostatin-null mice reveal PI3K and apoptotic pathways as myostatin targets

BACKGROUND: Myostatin (MSTN), a member of the TGF-β superfamily, has been identified as a negative regulator of skeletal muscle mass. Inactivating mutations in the MSTN gene are responsible for the development of a hypermuscular phenotype. In this study, we performed transcriptomic and proteomic ana...

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Detaylı Bibliyografya
Asıl Yazarlar: Chelh, Ilham, Meunier, Bruno, Picard, Brigitte, Reecy, Mark James, Chevalier, Catherine, Hocquette, Jean-François, Cassar-Malek, Isabelle
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2009
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2684550/
https://ncbi.nlm.nih.gov/pubmed/19397818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-10-196
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