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Lessons from comparative physiology: could uric acid represent a physiologic alarm signal gone awry in western society?

Uric acid has historically been viewed as a purine metabolic waste product excreted by the kidney and gut that is relatively unimportant other than its penchant to crystallize in joints to cause the disease gout. In recent years, however, there has been the realization that uric acid is not biologic...

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Detalhes bibliográficos
Main Authors: Johnson, Richard J., Sautin, Yuri Y., Oliver, William J., Roncal, Carlos, Mu, Wei, Sanchez-Lozada, L. Gabriela, Rodriguez-Iturbe, Bernardo, Nakagawa, Takahiko, Benner, Steven A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2684327/
https://ncbi.nlm.nih.gov/pubmed/18649082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00360-008-0291-7
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