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Homeostatic Role of Transforming Growth Factor-β in the Oral Cavity and Esophagus of Mice and Its Expression by Mast Cells in These Tissues

Transforming growth factor-β (TGF-β) is a pleiotropic growth factor; its overexpression has been implicated in many diseases, making it a desirable target for therapeutic neutralization. In initial safety studies, mice were chronically treated (three times per week) with high doses (50 mg/kg) of a m...

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Detalhes bibliográficos
Main Authors: Vitsky, Allison, Waire, James, Pawliuk, Robert, Bond, Arden, Matthews, Douglas, LaCasse, Emily, Hawes, Michael L., Nelson, Carol, Richards, Susan, Piepenhagen, Peter A., Garman, Richard D., Andrews, Laura, Thurberg, Beth L., Lonning, Scott, Ledbetter, Steve, Ruzek, Melanie C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2684179/
https://ncbi.nlm.nih.gov/pubmed/19406991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080723
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