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Disruption of Interleukin-1 Signaling Improves the Quality of Wound Healing

In this study, we investigated the role of interleukin (IL)-1 signaling in wound healing. IL-1 receptor type I (IL-1R) knockout (KO) mice showed reduced fibrosis in both cutaneous and deep tissue wounds, which was accompanied by a reduction in inflammatory cellular infiltration in cutaneous but not...

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Detalhes bibliográficos
Main Authors: Thomay, Alan A., Daley, Jean M., Sabo, Edmond, Worth, Patrick J., Shelton, Leslie J., Harty, Mark W., Reichner, Jonathan S., Albina, Jorge E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2684178/
https://ncbi.nlm.nih.gov/pubmed/19389930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080765
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