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Comparative analysis of module-based versus direct methods for reverse-engineering transcriptional regulatory networks

BACKGROUND: A myriad of methods to reverse-engineer transcriptional regulatory networks have been developed in recent years. Direct methods directly reconstruct a network of pairwise regulatory interactions while module-based methods predict a set of regulators for modules of coexpressed genes treat...

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Autors principals: Michoel, Tom, De Smet, Riet, Joshi, Anagha, Van de Peer, Yves, Marchal, Kathleen
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2684101/
https://ncbi.nlm.nih.gov/pubmed/19422680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-3-49
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