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A Role for SC35 and hnRNPA1 in the Determination of Amyloid Precursor Protein Isoforms

The β-amyloid peptide (Aβ) that accumulates in senile plaques in Alzheimer’s disease is formed by cleavage of the Amyloid Precursor Protein (APP). The APP gene has several intronic Alu elements inserted in either the sense or antisense orientation. In this study, we demonstrate that binding of SC35...

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Main Authors: Donev, Rossen, Newall, Alistair, Thome, Johannes, Sheer, Denise
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2684093/
https://ncbi.nlm.nih.gov/pubmed/17353911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.mp.4001971
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