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A Role for SC35 and hnRNPA1 in the Determination of Amyloid Precursor Protein Isoforms

The β-amyloid peptide (Aβ) that accumulates in senile plaques in Alzheimer’s disease is formed by cleavage of the Amyloid Precursor Protein (APP). The APP gene has several intronic Alu elements inserted in either the sense or antisense orientation. In this study, we demonstrate that binding of SC35...

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Detalhes bibliográficos
Main Authors: Donev, Rossen, Newall, Alistair, Thome, Johannes, Sheer, Denise
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2684093/
https://ncbi.nlm.nih.gov/pubmed/17353911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.mp.4001971
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