A carregar...
Cold-induced disruption of Na(+) channel slow inactivation underlies paralysis in highly thermosensitive paramyotonia
The Q270K mutation of the skeletal muscle Na(+) channel α subunit (Nav1.4) causes atypical paramyotonia with a striking sensitivity to cold. Attacks of paralysis and a drop in the compound muscle action potential (CMAP) are exclusively observed at cold. To understand the pathogenic process, we studi...
Na minha lista:
| Main Authors: | , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2009
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2683958/ https://ncbi.nlm.nih.gov/pubmed/19221125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.165787 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|