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Aldolase is essential for energy production and bridging adhesin-cytoskeletal interactions during parasite invasion of host cells

Apicomplexan parasites are obligate intracellular pathogens that rely on actin-based motility to drive host cell invasion. Prior in vitro studies implicated aldolase in coupling actin filaments to the cytoplasmic domains of surface adhesins in the parasite. Here, we tested the essentiality of this i...

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Detalhes bibliográficos
Main Authors: Starnes, G. Lucas, Coincon, Mathieu, Sygusch, Jurgen, Sibley, L. David
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683947/
https://ncbi.nlm.nih.gov/pubmed/19380114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2009.03.005
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