Sequence Conservation in Plasmodium falciparum α-Helical Coiled Coil Domains Proposed for Vaccine Development

BACKGROUND: The availability of the P. falciparum genome has led to novel ways to identify potential vaccine candidates. A new approach for antigen discovery based on the bioinformatic selection of heptad repeat motifs corresponding to α-helical coiled coil structures yielded promising results. To e...

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Bibliographic Details
Main Authors: Kulangara, Caroline, Kajava, Andrey V., Corradin, Giampietro, Felger, Ingrid
Format: Artigo
Language:Inglês
Published: Public Library of Science 2009
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683929/
https://ncbi.nlm.nih.gov/pubmed/19492090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005419
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