Atrial natriuretic peptide-stimulated Ca(2+) reabsorption in rabbit kidney requires membrane-targeted, cGMP-dependent protein kinase type II

Atrial natriuretic peptide (ANP) and nitric oxide (NO) are key regulators of ion and water transport in the kidney. Here, we report that these cGMP-elevating hormones stimulate Ca(2+) reabsorption via a novel mechanism specifically involving type II cGMP-dependent protein kinase (cGK II). ANP and th...

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Main Authors: Hoenderop, Joost G. J., Vaandrager, Arie B., Dijkink, Lisette, Smolenski, Albert, Gambaryan, Stepan, Lohmann, Suzanne M., de Jonge, Hugo R., Willems, Peter H. G. M., Bindels, René J. M.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 1999
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC26839/
https://ncbi.nlm.nih.gov/pubmed/10339545
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