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Evidence for the Nucleus Accumbens as a Neural Substrate of Heroin-Induced Immune Alterations

Administration of opioid drugs such as heroin produces several immunosuppressive effects, including decreases in natural killer (NK) cell activity, lymphocyte proliferative responses, and nitric oxide production. Interestingly, opioids have been shown to alter many immune parameters indirectly by mo...

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Detalhes bibliográficos
Main Authors: Saurer, Timothy B., Ijames, Stephanie G., Lysle, Donald T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Pharmacology and Experimental Therapeutics 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683780/
https://ncbi.nlm.nih.gov/pubmed/19258519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.108.148627
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