Ov-APR-1, an aspartic protease from the carcinogenic liver fluke, Opisthorchis viverrini: functional expression, immunolocalization and subsite specificity

The human liver fluke Opisthorchis viverrini is endemic in Thailand, Laos and Cambodia where long standing infection is associated with cancer of the bile ducts, cholangiocarcinoma. Here we describe a cathepsin D-like aspartic protease from the gut and other tissues in O. viverrini. Phylogenetic ana...

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Detalhes bibliográficos
Main Authors: Suttiprapa, Sutas, Mulvenna, Jason, Huong, Ngo Thi, Pearson, Mark S., Brindley, Paul J., Laha, Thewarach, Wongkham, Sopit, Kaewkes, Sasithorn, Sripa, Banchob, Loukas, Alex
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683748/
https://ncbi.nlm.nih.gov/pubmed/18996218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2008.10.013
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