Metabolomics of the interaction between PPAR-α and age in the PPAR-α-null mouse

Regulation between the fed and fasted states in mammals is partially controlled by peroxisome proliferator-activated receptor-α (PPAR-α). Expression of the receptor is high in the liver, heart and skeletal muscle, but decreases with age. A combined (1)H nuclear magnetic resonance (NMR) spectroscopy...

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Hlavní autoři: Atherton, Helen J, Gulston, Melanie K, Bailey, Nigel J, Cheng, Kian-Kai, Zhang, Wen, Clarke, Kieran, Griffin, Julian L
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683722/
https://ncbi.nlm.nih.gov/pubmed/19357638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2009.18
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