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Molecular dissection of the eukaryotic initiation factor 4E (eIF4E) export-competent RNP

The eukaryotic translation initiation factor 4E (eIF4E) controls gene expression through its effects on mRNA export and cap-dependent translation, both of which contribute to its oncogenic potential. In contrast to its translation function, the mRNA export function of eIF4E is poorly understood. Usi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Topisirovic, Ivan, Siddiqui, Nadeem, Lapointe, Vincent Leroux, Trost, Matthias, Thibault, Pierre, Bangeranye, Catherine, Piñol-Roma, Serafin, Borden, Katherine L B
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683702/
https://ncbi.nlm.nih.gov/pubmed/19262567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.53
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