Synaptic removal of diacylglycerol by DGKζ and PSD-95 regulates dendritic spine maintenance

Diacylglycerol (DAG) is an important lipid signalling molecule that exerts an effect on various effector proteins including protein kinase C. A main mechanism for DAG removal is to convert it to phosphatidic acid (PA) by DAG kinases (DGKs). However, it is not well understood how DGKs are targeted to...

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Hlavní autoři: Kim, Karam, Yang, Jinhee, Zhong, Xiao-Ping, Kim, Myoung-Hwan, Kim, Yun Sook, Lee, Hyun Woo, Han, Seungnam, Choi, Jeonghoon, Han, Kihoon, Seo, Jinsoo, Prescott, Stephen M, Topham, Matthew K, Bae, Yong Chul, Koretzky, Gary, Choi, Se-Young, Kim, Eunjoon
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683696/
https://ncbi.nlm.nih.gov/pubmed/19229292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.44
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